Myasthenia gravis:

Pseudoparalytic myasthenia gravis ( )

Myasthenia gravis describes an autoimmune neuromuscular disorder which disturbs the communication between the muscles and nerves. People with the disease suffer from a progressive weakness of their voluntary controlled muscles. Medication such as anticholinesterase agents and immunosuppressive drugs may help to reduce the symptoms. Sometimes surgery can be performed to control the disease.

Full Description

Myasthenia gravis is an autoimmune disease that causes a progressive weakness in the muscles under voluntary control. It occurs when the immune system attacks the n-acetylcholine receptor, an essential structure in the communication between nerves and muscles.

Symptoms

Palpitations, Pallor, Hair loss, Drowsiness, Dizziness, Shortness of breath, Burning in the throat, Cold feet, Chest pain, Cold hands, Brittleness of nails, Mouth ulcers, Tongue burning, Agitation, Feeling faint, Reduced appetite, Missed period, Menstruation disorder, Joylessness, Impairment of male potency, Tiredness, Moist and softened skin, Dry skin, Mood swings, Difficulty to concentrate, Weight gain, Sensitivity to cold, Hair loss, Less than 3 defecations per week, Hoarseness, Pallor, Muscle pain, Brittleness of nails, Numbness in the arm, Tiredness, Pallor, Disorientation regarding time or place, Tongue burning, Pain in the bones, Tiredness, Bone fracture, Pain in the limbs, Curvature of the spine, Tears, Eyelids sticking together, Face pain, Eye blinking, Abdominal pain, Flatulence, Diarrhea, Nausea, Foul smelling defecation, Bloated feeling in the stomach, Distended abdomen, Paralysis, Muscular weakness in the arm, Muscular weakness in the leg, Skin nodules, Itching of skin, Hair loss, Changes in the nails, Skin redness, Blue colored skin, Abdominal pain, Diarrhea, Fever, Pain in the limbs, Headache, Neck stiffness, Nausea, Shortness of breath, Fever, Lockjaw, Cramps, Muscle stiffness, Sweating, Vision impairment for near objects, Vision impairment, Abdominal pain, Diarrhea, Increased thirst, Pain of the anus, Back pain, Lower-back pain, Limited mobility of the back, Shortness of breath, Bloody cough, Cough, Chest pain, Shortness of breath, Chest pain, Chest tightness, Cough, Back pain, Breathing-related pains, Palpitations, Bold area among hair on the head, Joint pain, Oversensitivity to light, Shortness of breath, Skin rash, Skin redness, Tiredness, Weight loss, Swollen glands in the armpit, Swollen glands in the groin, Fever, Swollen glands in the neck, Sadness, Mood swings, Mouth ulcers, Joylessness, Itching of skin, Hair loss, Scar, Skin redness, Pain in the limbs, Joint pain, Skin rash, Headache, Tiredness, Paralysis, Fever, Neck stiffness, Blue colored skin, Diarrhea, Fever, Weight loss, Skin rash, Swollen glands in the neck, Swollen glands in the armpit, Swollen glands in the groin, Tiredness, Sweating, Night sweats, Leg swelling, Arm swelling, Limited mobility of the leg, Hand pain, Vision impairment, Vision impairment for near objects, Pain in the bones, Back pain, Fever, Weight loss, Sweating, Arm swelling, Joint pain, Bone fracture, Leg swelling, Dark urine, Urge to urinate, Frequent urination, Urination during the night, Dribbling after urination, Painful urination, Decreased urine stream, Delayed start to urination, Impairment of male potency, Pain in the bones, Abdominal pain, Blue spot on skin, Pallor, Dark urine, Fever, Chills, Cough, Abdominal pain, Sweating, Blackening of vision, Disorientation regarding time or place, Yellow colored skin, Shortness of breath, Burning eyes, Burning in the throat, Cough, Eye redness, Fever, Itching eyes, Pain in the limbs, Runny nose, Skin rash, Sore throat, Swollen glands in the armpit, Swollen glands in the groin, Swollen glands in the neck, Tiredness, Oversensitivity to light, Facial swelling, Flaking skin, Pallor, Yellow colored skin, Yellowish discoloration of the white part of the eye, Visual field loss, Facial paralysis, Impaired balance, Headache, Paralysis, Tiredness, Eye pain, Mood swings, Aggressiveness, Vision impairment, Increased drive, Sleeplessness, Difficulty to concentrate, Mood swings, Agitation, Aggressiveness, Feeling of pressure in the ear, Fever, Impaired hearing, Facial paralysis, Face pain, Headache, Swollen glands in the neck, Earache, Reduced appetite, Cough, Runny nose, Tiredness, Pain in the limbs, Shortness of breath, Chest pain, Chest tightness, Cough, Night cough, Feeling faint, Heart murmur, Palpitations, Blue colored skin, Irregular mole, Scar, Skin nodules, Skin thickening, Nausea, Vomiting, Dizziness, Muscle pain, Pain in the calves, Tremor on movement, Limited mobility of the leg, Physical inactivity, Joint instability, Muscle weakness, Muscular weakness in the arm, Muscular weakness in the leg, Difficulty in swallowing, Drooping eyelid, Muscular weakness in the arm, Muscular weakness in the leg

Medical Conditions

Myasthenia gravis is a type of autoimmune disorder that occurs when the immune system mistakenly attacks healthy tissue. In people with myasthenia gravis, the immune system produces antibodies that mistakenly block the muscle cells from receiving messages from the nerve cells. However, the exact cause of the misguidance of the immune system is unknown. Antibodies against the thymus, which often occur due to a tumor in the thymus, seem to play a role in certain cases. It may affect people at any age. It is more prevalent in women than in men. The main symptom of myasthenia gravis is weakness of all voluntary controlled muscles (the heart muscle and smooth muscle cells, which are located in a variety of inner organs, do not count as such). It therefore may lead to symptoms such as general loss of muscle strength, difficulty with breathing, chewing, talking, swallowing, further a drooping head, facial paralysis, fatigue, and hoarseness. At early stage the disease typically causes first trouble with the eye muscles such as double vision and drooping of the eyelids.

Treatment

There is no complete cure for Myasthenia gravis. However, proper medical treatment can help to reduce associated symptoms. Some doctors suggest changes in lifestyle, for example having adequate rest and avoiding stress and heat exposure which can worsen the symptoms. Medication is often used to relieve symptoms. For example, anticholinesterase agents like pyridostigmine or neostigmine may improve neuromuscular transmission and increase muscle strength. Immunosuppressive drugs like prednisone, cyclosporin, mycophenolate mofetil, azathioprine and tacrolimus can be used to suppress the production of abnormal antibodies. In some cases a surgical removal of the thymus can change the process for the better.